One stormy night a strange visitor comes to the Murry house and beckons Meg, her brother, Charles Wallace, and their friend Calvin O’Keefe on a most dangerous and fantastic journey—a journey that will threaten their lives and our universe.

Meg Murry and her brother Charles Wallace, along with their neighbor, Calvin O’Keefe, find “dragons” in a vegetable garden. But when Charles Wallace falls ill, Meg, Calvin, and their teacher, Mr. Jenkins, must travel inside C.W. to make him well, and save the universe from the evil Echthros.

The Murry and O’Keefe families enlist the help of the unicorn, Gaudior, to save the world from imminent nuclear war.

Meg Murry, now in college, time travels with her twin brothers, Sandy and Dennys, to a desert oasis that is embroiled in war.

Polly O’Keefe has recently come to live in the country with her grandparents, the famous scientists Alex and Kate Murry, when she wanders into a time 3,000 years before her own.